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  • 主办单位:
    中国光学工程学会清华大学上海理工大学
  • 名誉主编: 庄松林 院士
  • 国际主编: 顾敏 院士
  • 主       编:
    孙洪波 教授仇旻 教授
  • 创       刊:2020年3月
  • ISSN:2662-1991
最新上线
Pulsed polarized vortex beam enabled by metafiber lasers
Chenxi Zhang, Lei Zhang, He Zhang, Bo Fu, Jiyong Wang, Min Qiu
 doi: 10.1186/s43074-024-00151-6
Abstract(0) PDF(0)
Abstract:
Pulsed polarized vortex beams, a special form of structured light, are generated by tailoring the light beam spatiotemporally and witness the growing application demands in nonlinear optics such as ultrafast laser processing and surface plasma excitation. However, existing techniques for generating polarized vortex beams suffer from either low compactness due to the use of bulky components or limited controlment of pulse performance. Here, an all-fiber technique combining plasmonic metafibers with mode conversion method is harnessed to generate high-performance pulsed polarized vortex beams. Plasmonic metafibers are utilized as saturable absorbers to produce Q-switched pulses with micro-second duration, while the offset splicing method is employed to partially convert the fundamental transverse mode (LP$ _{01} $) to higher-order mode (LP$ _{11} $). Eventually, a polarized vortex beams laser is achieved at the telecom band with a repetition frequency of 116.0 kHz. The impact of geometrical parameters including period of metafibers and offset of splicing on the spatiotemporal properties of pulsed polarized vortex beams is systematically investigated. Our findings could pave the way for design, control and generation of all-fiber pulsed polarized vortex beams, and also offer insights into the development of other types of structured laser sources.
Characterization of cancer-associated adipocytes by Raman spectroscopy and trajectory inference
Nicolas Goffin, Emilie Buache, Nathalie Lalun, Marion Fernandes, Ines Miguel, Catherine Muller, Charlotte Vaysse, Landry Blanc, Cyril Gobinet, Olivier Piot
 doi: 10.1186/s43074-024-00146-3
Abstract(2) PDF(1)
Abstract:
Cancer-associated adipocytes (CAAs) have emerged as pivotal players in various cancers, particularly in such as breast cancer, significantly influencing their progression and therapy resistance. Understanding the adipocytes/cancer cells crosstalk is crucial for effective treatment strategies. Raman spectroscopy, a label-free optical technique, offers potential for characterizing biological samples by providing chemical-specific information. In this study, we used Raman spectroscopy and Trajectory Inference methods, specifically the Partition-based graph abstraction algorithm, to investigate the interactions between 3T3-L1 differentiated adipocytes and MDA-MB-231 breast cancer cells in a 2D co-culture model. We demonstrate the existence of subpopulations of adipocytes and the molecular changes associated with CAAs phenotype. This work contributes to understanding the role of CAAs in breast cancer progression and may guide the development of targeted therapies disrupting this interaction.
Three-dimensional computer holography with phase space tailoring
Runze Zhu, Lizhi Chen, Jiasheng Xiao, Hao Zhang
 doi: 10.1186/s43074-024-00149-0
Abstract(11) PDF(4)
Abstract:
Computer holography is a prominent technique for reconstructing customized three-dimensional (3D) diffraction fields. However, the quality of optical reconstruction remains a fundamental challenge in 3D computer holography, especially for the 3D diffraction fields with physically continuous and extensive depth range. Here, we propose a 3D computer-generated hologram (CGH) optimization framework with phase space tailoring. Based on phase space analysis of the space and frequency properties in both lateral and axial directions, the intensity of the 3D diffraction field is adequately sampled across a large depth range. This sampling ensures the reconstructed intensity distribution to be comprehensively constrained with physical consistency. A physics-informed loss function is constructed based on the phase space tailoring to optimize the CGH with suppression of vortex stagnation. Numerical and optical experiments demonstrate the proposed method significantly enhances the 3D optical reconstructions with suppressed speckle noise across a continuous and extensive depth range.
Near-field strong coupling and entanglement of quantum emitters for room-temperature quantum technologies
Daniel D. A. Clarke, Ortwin Hess
 doi: 10.1186/s43074-024-00148-1
Abstract(14) PDF(0)
Abstract:
In recent years, quantum nanophotonics has forged a rich nexus of nanotechnology with photonic quantum information processing, offering remarkable prospects for advancing quantum technologies beyond their current technical limits in terms of physical compactness, energy efficiency, operation speed, temperature robustness and scalability. In this perspective, we highlight a number of recent studies that reveal the especially compelling potential of nanoplasmonic cavity quantum electrodynamics for driving quantum technologies down to nanoscale spatial and ultrafast temporal regimes, whilst elevating them to ambient temperatures. Our perspective encompasses innovative proposals for quantum plasmonic biosensing, driving ultrafast single-photon emission and achieving near-field multipartite entanglement in the strong coupling regime, with a notable emphasis on the use of industry-grade devices. We conclude with an outlook emphasizing how the bespoke characteristics and functionalities of plasmonic devices are shaping contemporary research directives in ultrafast and room-temperature quantum nanotechnologies.